Not being able to replicate those performances, though, has resulted in frustration for Santana. The right-hander, winner of a career-high 17 games in 2010, is 0-3 with a 5.51 ERA in five starts this season. He'll try to overcome a rough start when the Angels open up a three-game series on Friday against lefty David Price and the Rays.
The Angels are looking for help from the bottom of their rotation. While Weaver and Haren have been nearly untouchable, the rest of the team's starters are 3-5 with a 5.52 ERA in 13 outings.
Santana, who has won at least 12 games in four of the last six seasons, has given up 11 runs in his past 11 innings. He allowed five runs over seven innings in his last outing, a 5-0 loss to the Red Sox.
"Everything feels good," Santana said. "My fastball, slider, changeup are all working. It seems like I make one bad pitch and it gets hit."
Santana could use some added run support. The Angels have scored 11 runs in his five starts, including a total of just three in his three losses.
Price, 3-2 with a 3.19 ERA in five starts this season, is pitching on an extra day's rest after the Rays' series opener against the Twins on Tuesday was postponed and was made up as part of a split doubleheader on Thursday.
Price is coming off a four-run outing over eight innings in a win over the Blue Jays and is two starts removed from an eight-inning gem against the White Sox, in which he allowed just four hits and no runs.
Angels: Bullpen rebounding from rough start
After a tough stretch in the first week of the season, the Angels' bullpen has been stellar. The club's relievers gave up 11 earned runs in the first five games (18 1/3 innings), but they have surrendered just 10 earned runs in the 20 games since (56 1/3 innings). Arguably the most noteworthy contributor has been Jordan Walden. The right-hander surrendered his first run of the season on Wednesday and has surrendered just five hits in 11 innings of work.
Rays: Longoria close to return
The Rays will soon have their Gold Glove third baseman back. Evan Longoria is expected to come of the disabled list on Tuesday, manager Joe Maddon said.
Longoria -- on the disabled list since April 2 with a strained oblique -- began a five-game rehab assignment at Double-A Montgomery on Thursday, where the club hopes to get the All-Star about 15 at-bats before he makes his return on Tuesday against the Blue Jays.
Ben Zobrist drove in eight runs in Thursday's 15-3 win over the Twins in the early game, and then plated two more in the nightcap. Zobrist finished 8-for-14 in the three-game series with two home runs, three doubles, a triple, 13 RBIs and six runs scored.
Haren's outing on Wednesday was the Angels' 19th quality start in 25 games. Johnny Damon enters the series riding a 16-game hitting streak. The veteran outfielder went a combined 4-for-9 with three runs scored and one RBI in the Rays' sweep of yesterday's doubleheader in Minnesota, extending his franchise record for longest hitting streak in April.